Cardioprotective effect of curcumin against doxorubicin-induced myocardial toxicity in albino rats

Cardioprotective effect of lipistat against doxorubicin induced myocardial toxicity in albino rats.

Preventive role of lipistat against doxorubicin induced myocardial toxicity in rats has been reported. Cardiotoxicity was produced by doxorubicin administration (15 mg/kg for 2 weeks). Lipistat (350 mg/kg, orally) was administered as pretreatment for 2 weeks and then for 2 weeks alternated with doxorubicin. The general observations, mortality, histopathology, biomarker enzymes like lactate dehy...

Cardio protective Effect of Boerhaavia diffusa against Doxorubicin-induced myocardial toxicity in Albino Rats

Doxorubicin is Anrthacycline derivative and most active cytotoxic agent in current use. It is been using to treat various malignancies but the clinical usefulness has been limited due to its specific cardiac toxicity. The main objective is to study the preventive role of ethanolic extract of whole plant of Boerhaavia diffusa (EEBD) against doxorubicin (Dox) induced myocardial toxicity in rats. ...

Cardioprotective Effect of Naringin against Doxorubicin Induced Cardiomyopathy in Rats

Phytoconstituents Analysis by Gc-ms, Cardioprotective and Antioxidant Activity of Buchanania Axillaris against Doxorubicin-induced Cardio Toxicity in Albino Rats

Buchanania axillaries(Anacardiaceae) is a traditional herbal medicine , the leaves are used to treat many diseases including cardiotoxicity.’The present study was designed to scientifically evaluate the cardioprotective potential of the ethanol extract of Buchanania axillaries(BA), on Doxorubicin (DOX) induced cardiotoxicity, in albino rats. DOX is one of the most effective chemotherapeutic dru...

Therapeutic effect of valsartan against doxorubicin-induced renal toxicity in rats

Objective(s): Doxorubicin (DXR)-induces glomerular atrophy and fibrosis in rat kidneys. The objective of the current study was to investigate the protective effects of valsartan on DXR-induced glomerular toxicity and its mechanisms of actions in rats. Materials and Methods: Male Sprague-Dawley (SD) rats were divided into four groups, and each group contains ten rats. First group was control and...